糖尿病黄斑浮腫（DME） Diabetic Macular Edemaとその治療方法　最近の進展

日本では2022年6月に血管内皮増殖因子（VEGF）阻害薬ブロルシズマブ硝子体注射（IVBr）が糖尿病黄斑浮腫（DME）への適応追加を取得したそうです。

1. ブロルシズマブのIOI発生率、DMEでは9.1％ 症例から見えてきた患者の特徴と早期受診の重要性 2024年04月08日 17:45 MedicalTribune

糖尿病黄斑浮腫（DME） Diabetic Macular Edema

1. Understanding Diabetic Macular Edema (21:06)　American Society of Retina Specialists チャンネル登録者数 3450人ホスト役の医師が専門家の医師にインタビューして説明してもらう形式

糖尿病黄斑浮腫 Diabetic Macular Edemaの治療

New laser treatment for diabetic macular oedema (DMO) (55:27) Macular Society チャンネル登録者数 6670人

• If center of the retina on OCT is 400 microns or more: treat with anti-VEGs. if cener of the retina on OCT is less than 400 microns: treat with macular laser because in a thinner macula, laser works well and is much less expenesive.(16:02)
• anti-VEGFを用いた治療の概説(17:47)
• macular laser治療の説明(20:22)
• SMLを用いた治療効果を検証する大規模多施設臨床試験DIAMONDS(25:24)

A subthreshold micropulse laser (SML) is a relatively new tissue-sparing laser technique; it avoids protein coagulation and prevents retinal scars, allowing the preservation of retinal anatomy and function [30].

Treatment of Macular Edema in Vascular Retinal Diseases: A 2021 Update J Clin Med. 2021 Nov; 10(22): 5300. Published online 2021 Nov 15. doi: 10.3390/jcm10225300 PMCID: PMC8619917 PMID: 34830582

Treatment of Macular Edema in Vascular Retinal Diseases: A 2021 Update

Macular edema (ME) is associated with various conditions; however, the main causes of ME are retinal vein occlusion (RVO) and diabetes. Laser photocoagulation, ...

www.ncbi.nlm.nih.gov

参考

1. Edema (wikipedia) also spelled oedema, and also known as fluid retention, dropsy, hydropsy and swelling, is the build-up of fluid in the body’s tissue.