大腸癌とOSNA

未分類

2024.03.05

OSNAの利用

The OSNA (One-Step Nucleic Acid Amplification) assay is a RT-PCR-based technique for detecting CK19 mRNA. It is a quantitative, fast, and standardised assay, and it has been validated for lymph node molecular analysis in breast and CRC [11,12,13].

Lymph Node Molecular Analysis with OSNA Enables the Identification of pT1 CRC Patients at Risk of Recurrence: A Multicentre Study
This study focuses on very-early-stage colorectal cancer (CRC), pT1, frequently diagnosed under the umbrella of CRC screening programs. There is a great deal of...
www.ncbi.nlm.nih.gov

A novel technique for pathological examination, OSNA, uses the reverse transcription loop-mediated isothermal amplification method to amplify CK19 mRNA.

Role of one-step nucleic acid amplification in colorectal cancer lymph node metastases detection
Current histopathological staging procedures in colorectal cancer (CRC) depend on midline division of the lymph nodes (LNs) with one section of hematoxylin and ...
www.ncbi.nlm.nih.gov

がんリンパ節転移診断システム（OSNA™法）遺伝子増幅検出装置 RD-200/100i　SYSMEX
OSNA in colorectal cancer　SYSMEX
One Step Nucleic Acid Amplification (OSNA) – a new method for lymph node staging in colorectal carcinomas　Published: 06 September 2010 https://translational-medicine.biomedcentral.com/articles/10.1186/1479-5876-8-83
Molecular Lymph Node Staging with One-Step Nucleic Acid Amplification and its Prognostic Value for Patients with Colon Cancer: The First Follow-up Study　https://link.springer.com/article/10.1007/s00268-020-05949-6