chiasama キアズマとは? 減数分裂 細胞生物学

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In cell biology, a chiasma (plural: chiasmata) is the point where two homologous (non-sister) chromatids exchange genetic material during the process of meiosis. This exchange occurs through a process called crossing over.

Role of Chiasma in Meiosis

  • Chiasmata are formed during prophase I of meiosis, specifically in the pachytene stage.
  • They represent the physical manifestation of the crossover between homologous chromosomes, which involves the reciprocal exchange of genetic segments.
  • This exchange of genetic material is crucial for generating genetic diversity in gametes.

Formation of Chiasma

  1. Synapsis: Homologous chromosomes (each consisting of two sister chromatids) pair up along their lengths, forming a structure called a bivalent or tetrad.
  2. Crossing Over: The non-sister chromatids within the homologous chromosomes physically break and rejoin at specific points. These points are called chiasmata.
  3. Chiasma Formation: The resulting cross-shaped structure, where the chromatids are physically connected, is the chiasma. It holds the homologous chromosomes together until they are separated during anaphase I of meiosis.

Importance of Chiasma

  • Chiasmata are critical for genetic recombination, which shuffles alleles between homologous chromosomes, creating new combinations of genes.
  • They also ensure the proper alignment and separation of homologous chromosomes during meiosis I, preventing errors in chromosome distribution.

In summary, a chiasma is a crossover point between homologous chromatids, playing an essential role in genetic diversity and chromosome segregation during meiosis.